CaptainJosiahNewmanrunstheneuro-psychiatricwardofanArizonadeserthospitalduringWorldWarII.HeoftenusesCaptainJosiahNewmanrunstheneuro-psychiatricwardofanArizonadeserthospitalduringWorldWarII.Heoftenusesunconventionalmeansandpeopletomatch,includinghisneworderly,JacksonLeibowitz.AmongthepatientsintheirwardisthesuicidalColonelBliss,whoeventuallyclimbsatopawatertower,andabattle-scarredcorporalnamedTompkinswhorevealsunderthespellofsodiumpentothalthesourceofhisdistress.NewmanalsoassistsinthemaritallovelifeofCaptainWinstonwhileenjoyingaflirtationortwowithhisownchiefnurse,LieutenantCorum.
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